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DEPARTMENT OF VETERINARY MICROBIOLOGY

Salient Achievements:

  1. Live attenuated cell culture vaccine against sheep pox was developed using Karnal strain of sheep pox virus.
  2. Vaccine for protection of poultry against salmonellosis and a process for preparing the same (Patents, US 6,605, 285 B2 (Aug, 12, 2003) and India-189049-96 (March, 01, 2001)
  3. Autogenous vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
  4. IgY based passive immunotherapy against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
  5. Inactivated cell culture vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
  6. Immune complex vaccine against hydropericardium syndrome virus (fowl adenovirus) in broiler birds.
  7. Cell culture vaccine against Marek’s disease and Infectious bursal disease in poultry.
  8. Serological and molecular diagnostic tests for goat pox and sheep pox in goat and sheep, Newcastle disease, Fowl pox, Inclusion body hepatitis/hydropericardium syndrome, Infectious bursal disease in poultry and parvovirus infection in dogs.
  9. Congo red binding test for detection of pathogenicity of Escherichia coli strains in poultry.
  10. A competitive ELISA test was developed for specific detection of antibodies to Haemorrhagic septicaemia in sera of cattle, pigs, sheep and goats.
  11. Anatomical studies on the Nervous system of buffalo and goat.
  12. To detect the presence of urea in adulterated/ synthetic milk, a strip test has been developed. The test is sensitive enough to detect urea at a concentration of 0.1% in milk in only one minute.
  13. Immunodiagnostic tests like ELISA, rider immunoassay (RIA), coagglutination (COAT), counter current Immunoelectrophoresis (CIE), fluorescent antibody test (FAT) have been standardized and carried out for the diagnosis of Infectious diseases, viz. infectious bursal disease, canine parvovirus infection, new castle, rota virus infection and salmonellosis.
  14. A Marek’s disease virus strain isolated locally from an apparently healthy bird was attenuated in chicken embryo fibroblast cell culture. The virus at its 20th passage level was used as a vaccine and the protection afforded was comparable to other available MD vaccines.
  15. Salmonella Toxoid afford 100% protection in mice.
  16. Congo red binding test for detection of pathogenecity of Escherichia coli strains in poultry developed.
  17. Studies based on serotypes of E.coli and antibiotic sensitivity pattern in colibacillosis in poultry were determined.
  18. Enterotoxin and four novel cytotoxins of Salmonella were purified and characterized.
Dr. Rajesh Kumar, Professor & Head
Selected Research Publications

  1. Saxena, A., Kumar R. and Saxena, M. K. (2017). Vaccination with Salmonella Typhi recombinant outer membrane protein 28 induces humoral but non-protective immune response in rabbit. Veterinary World, 10:946-949.
  2. Rani, V., Kumar, R., Upadhyay, A. K. and Kumar, M. (2012). Therapeutic Efficacy of Chicken Egg Yolk Immunoglobulins against hydropericardium syndrome in broiler Chickens. Indian Journal of Animal Sciences, 82(6):552-556.
  3. Kumar, R., Kumar, V., Asthana, M., Shukla, S. K. and Chandra, R. (2010). Isolation and Identification of a Fowl Adenovirus from Wild Black Kites (Milvus migrans). Journal of Wildlife Diseases 46(1):272-276.
  4. Kumar, R. and Chandra, R. (2004). Studies on structural and immunogenic polypeptides of hydropericardium syndrome virus by SDS-PAGE and western blotting. Comparative Immunology, Microbiology and Infectious Diseases, 27(3):155-161.
  5. Kumar, R., Chandra, R. and Shukla, S. K. (2003). Isolation of etiological agent of hydropericardium syndrome in chicken embryo liver cell culture and its serological characterization. Indian Journal of Experimental Biology, 41(8):821-826.

Dr. Anuj Tewari, Assistant Professor
Research Areas/areas of interests

  1. Multiplex assays for detection of viral/bacterial infections
  2. Epidemiology of Bluetongue and PPR

Selected Research Publications

  1. Anuj Tewari, Beenu Jain, Prakash S Dhamannapatil and Mumtesh Kumar Saxena (2018). Biofilm Resistance to Antimicrobial Agents and Novel Approaches to Combat Biofilm Mediated Resistance in Bacteria. EC Microbiology 14 (3):71-77
  2. SushilaMaan, Anuj Tiwari, Deepika Chaudhary, Anita Dalal, Nitish Bansal, Vinay Kumar, KanishtBatra, Aman Kumar, Naresh Kumar Kakker and Narender Singh Maan (2017) A comprehensive study on seroprevalence of bluetongue virus in Haryana state of India.Veterinary World, 10(12): 1464-1470.
  3. Vinay Kumar, Aman Kumar, Ashish Debnath, Kanista Batra, Nitish Bansal, Akhil Kumar Gupta, Anuj Tewari, Sushila Maan (2015) “Development of real time PCR assay for diagnosis of Brucella spp”. Haryana Vet. 54 (2): 99-102.
  4. S. K. Dash, K. Kumar, A. Tewari, A. Goel, A. K. Bhatia ( 2012) Detection of Rotavirus from hospitalized diarrheic children in Uttar Pradesh, India. Indian Journal of Microbiology 52 (3): 472-477.
  5. A. Tewari, S.K. Dash, B. Jain and A.K. Bhatia (2012) Detection of P1 type of bovine rotavirus using nested multiplex PCR in Mathura, India. Journal of Animal Research, 2 (2):179-185.

Dr. Jubeda Begum, Assistant Professor

Research Areas/areas of interests

  1. Diagnostics and vaccines for bacterial infections in livestock

Selected Research Publications

  1. Ameliorative effect of urosolic acid on renal fibrosis in adenine- induced chronic kidney disease in rats. Richa Thakur, Anshuk Sharma, Madhu CL, Jubeda Begum, Dhirendra Kumar, KarikalanMathesh, Thakur Uttam Singh, Dinesh Kumar. Biomedicine and Biopharmacy. Accepted on 27th February 2018
  2. Jubeda Begum, Pranabananda Das, MadhuCholenahalliLingaraju. Molecular and histopathological evaluation of the efficacy of Saponified and Freund’s incomplete adjuvantedparatuberculosis killed vaccine in murine model. Indian Journal Animal Research. Indian J. Anim. Res., 51 (3) 2017 : 510-517
  3. Jubeda Begum, T. K. Dutta, Parimal Roy Choudhary, Rajesh Chandra, Zomuankima Varte (2015) Antimicrobial assay of shigatoxigenic E. Coli (STEC) and enteropathogenic E. Coli (EPEC) isolated from diarrhoeic faecal samples of piglets and infants in Mizoram. Indian journal of animal sciences 85(10):1067-1072.
  4. Madhu C. Lingaraju, Nitya N. Pathak, Jubeda Begum, Venkanna Balaganur, Rafia A. Bhat, Mahendra Ram, Dhirendra Kumar, Dinesh Kumar, Surendra K. Tandan (2015). Betulinic acid negates oxidative lung injury in surgical sepsis model. Journal of Surgical Research. 193: 856-867.
  5. Jubeda Begum, T.K. Dutta, Rajesh Chandra, Parimal Roy Choudhary, Zomuankima Varte and Molalegne Bitew (2014). Molecular and phenotypic characterization ofshigatoxigenic Escherichia coli (STEC) and Enteropathogenic E. coli (EPEC) from piglets and infants associated with diarrhea in Mizoram, India. African Journal of Biotechnology, 13:1452-1461.